Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | CDC25C | P30307 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196064 | 0.91 | MIF (0.45) | MAPTALDH1A1HPGDCDC25ALMNA | |
| SCHEMBL22331115 | 0.87 | CDC25A (0.62) | MAPTALDH1A1HPGDCYP3A4CDC25A | |
| SCHEMBL22331118 | 0.87 | CDC25A (0.62) | MAPTALDH1A1HPGDCYP3A4CDC25A | |
| SCHEMBL19196313 | 0.84 | MAPT (0.58) | MAPTALDH1A1CYP3A4LMNAKDM4E | |
| SCHEMBL17037974 | 0.83 | HSD11B1 (0.47) | MAPTALDH1A1HPGDCYP3A4KDM4E | |
| SCHEMBL17525289 | 0.82 | MAOB (0.64) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL19196314 | 0.80 | MAOB (0.42) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL19196345 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL19196315 | 0.75 | MAOB (0.45) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL12611517 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | SQOR, TXN2, TXNRD1 | MAPT 1297/4885ALDH1A1 533/4885HPGD 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.