Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204899 | 0.86 | P2RX7 (0.61) | P2RX7HTTALDH1A1LMNAPKM | |
| SCHEMBL29601383 | 0.83 | P2RX7 (0.61) | P2RX7ALDH1A1PKMPTGS1PTGS2 | |
| SCHEMBL29601293 | 0.80 | ALDH1A1 (0.48) | HTTALDH1A1LMNATSHRMAPT | |
| SCHEMBL29601252 | 0.77 | P2RX7 (0.56) | P2RX7ALDH1A1LMNAMAPTHSP90AA1 | |
| SCHEMBL30677327 | 0.75 | XDH (0.54) | HTTALDH1A1TSHRMAPTCCNE2 | |
| SCHEMBL28802463 | 0.74 | P2RX7 (0.47) | P2RX7HTTALDH1A1MAPTCXCL8 | |
| SCHEMBL27991603 | 0.73 | PI4KA (0.59) | HTTALDH1A1LMNATSHRMAPT | |
| SCHEMBL19746470 | 0.73 | P2RX7 (0.46) | P2RX7HTTALDH1A1LMNAPKM | |
| SCHEMBL3821565 | 0.73 | YTHDC1 (0.57) | CCNE2CCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL5440560 | 0.72 | CDK2 (0.43) | P2RX7MAPTCCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |