Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204899 | 0.87 | P2RX7 (0.61) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL28802463 | 0.86 | P2RX7 (0.47) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL19745997 | 0.80 | L3MBTL1 (0.48) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL29601383 | 0.79 | P2RX7 (0.61) | P2RX7ALDH3A1NOD1ALDH1A1PTGS2 | |
| SCHEMBL29601246 | 0.73 | P2RX7 (0.57) | P2RX7NOD1HTTLMNAALDH1A1 | |
| SCHEMBL27902479 | 0.71 | HTT (0.53) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL15136400 | 0.71 | XDH (0.62) | ALDH3A1L3MBTL1NOD1POLBHTT | |
| SCHEMBL30173097 | 0.68 | CDK1 (0.50) | — | |
| SCHEMBL15426836 | 0.68 | L3MBTL1 (0.53) | ALDH3A1L3MBTL1NOD1POLBHTT | |
| SCHEMBL27885507 | 0.68 | CYP1A2 (0.47) | ALDH3A1L3MBTL1NOD1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-02 | — | — | US | disclosed |
| WO-2017223406-A1 | COMPLEXES FOR NUCLEOPHILIC, RADICAL, AND ELECTROPHILIC POLYFLUOROALKYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | NBAS, PFAS, PCBP1 | P2RX7 3515/4885ALDH3A1 2219/4885L3MBTL1 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.