Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204899 | 0.88 | P2RX7 (0.61) | P2RX7L3MBTL1NOD1POLBALDH3A1 | |
| SCHEMBL19746470 | 0.86 | P2RX7 (0.46) | P2RX7L3MBTL1NOD1POLBALDH3A1 | |
| SCHEMBL19745997 | 0.81 | L3MBTL1 (0.48) | P2RX7L3MBTL1NOD1POLBALDH3A1 | |
| SCHEMBL3268044 | 0.78 | ADORA2A (0.59) | ALDH1A1 | |
| SCHEMBL4724390 | 0.77 | L3MBTL1 (0.51) | L3MBTL1NOD1POLBALDH3A1HTT | |
| SCHEMBL9368148 | 0.77 | MPO (0.44) | L3MBTL1NOD1POLBALDH3A1HTT | |
| SCHEMBL15136400 | 0.77 | XDH (0.62) | L3MBTL1NOD1POLBALDH3A1HTT | |
| SCHEMBL4767205 | 0.76 | ALDH1A1 (0.42) | L3MBTL1NOD1POLBALDH3A1HTT | |
| SCHEMBL29601383 | 0.75 | P2RX7 (0.61) | P2RX7NOD1ALDH3A1ALDH1A1 | |
| SCHEMBL29601246 | 0.74 | P2RX7 (0.57) | P2RX7NOD1HTTHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850355-A | 9-sulfonyl-9H-purine derivatives, and preparation method and use thereof | UNIV SICHUAN | 2013-01-02 | — | — | CN | disclosed |