Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560322 | 0.69 | NOS1 (0.32) | NOS1 | |
| SCHEMBL11170137 | 0.62 | MEN1 (0.36) | — | |
| SCHEMBL3980437 | 0.61 | AKR1B1 (0.47) | NOS1 | |
| SCHEMBL17338970 | 0.60 | TSHR (0.41) | — | |
| SCHEMBL21181617 | 0.58 | GABRP (0.46) | — | |
| SCHEMBL6737816 | 0.55 | GABRP (0.41) | — | |
| SCHEMBL19410958 | 0.53 | NOS1 (0.59) | NOS1 | |
| SCHEMBL6649529 | 0.53 | LMNA (0.42) | — | |
| SCHEMBL819619 | 0.52 | TSHR (0.68) | — | |
| SCHEMBL18825349 | 0.52 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143027-A1 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11306094-B2 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2022-04-19 | — | — | US | disclosed |
| US-20200283443-A1 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2020-09-10 | — | — | US | disclosed |
| US-10570134-B2 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2020-02-25 | — | — | US | disclosed |
| US-20190270745-A1 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2019-09-05 | — | — | US | disclosed |
| US-10336758-B2 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2019-07-02 | — | — | US | disclosed |
| US-10059710-B2 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2018-08-28 | — | — | US | disclosed |
| US-20180134711-A1 | New stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2018-05-17 | — | — | US | disclosed |
| US-20170233394-A1 | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2017-08-17 | — | — | US | disclosed |