Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694720 | 0.85 | — | — | |
| SCHEMBL5064786 | 0.75 | DHFR (0.46) | MTHFD1DHFR | |
| SCHEMBL7757766 | 0.73 | DHFR (0.31) | DHFR | |
| SCHEMBL3980437 | 0.72 | AKR1B1 (0.47) | NOS1DHFR | |
| SCHEMBL4616964 | 0.70 | MTHFD1 (0.47) | MTHFD1DHFR | |
| SCHEMBL19206626 | 0.69 | NOS1 (0.34) | NOS1 | |
| SCHEMBL21181617 | 0.56 | GABRP (0.46) | — | |
| SCHEMBL12958941 | 0.55 | NOS1 (0.37) | NOS1NOS3NOS2 | |
| SCHEMBL31315883 | 0.54 | NOS1 (0.43) | NOS1NOS3NOS2 | |
| SCHEMBL20374994 | 0.54 | NOS1 (0.45) | NOS1MTHFD1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524066-B | (6S) 5 methyl tetrahydrofolate or its salt composite and its preparation and application | 连云港金康和信药业有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-105524066-A | (6S)-5-methyltetrahydrofolic acid or (6S)-5-methyltetrahydrofolate composition and preparation method and use thereof | LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO LTD | 2016-04-27 | — | — | CN | claimed |
| CN-105524066-B | (6S) 5 methyl tetrahydrofolate or its salt composite and its preparation and application | 连云港金康和信药业有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-105524066-A | (6S)-5-methyltetrahydrofolic acid or (6S)-5-methyltetrahydrofolate composition and preparation method and use thereof | LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO LTD | 2016-04-27 | — | — | CN | disclosed |
| WO-2016034145-A1 | COMPOSITION OF (6S)-5-METHYL TETRAHYDROFOLIC ACID OR SALT THEREOF AS WELL AS PREPARATION THEREFOR AND APPLICATION THEREOF | 连云港金康和信药业有限公司 | 2016-03-10 | — | — | WO | disclosed |