Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553844 | 0.82 | RORC (0.49) | GLARORCTSHR | |
| SCHEMBL16553618 | 0.81 | MTNR1A (0.49) | GLAALDH1A1MAPK1L3MBTL1MTNR1A | |
| SCHEMBL14822091 | 0.72 | GLA (0.55) | GLAALDH1A1MAPK1L3MBTL1SLC6A3 | |
| SCHEMBL11996930 | 0.67 | GLA (0.52) | GLAALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL11627496 | 0.67 | MTNR1A (0.57) | ALDH1A1MAPK1MTNR1AKMT2ATSHR | |
| SCHEMBL12450088 | 0.66 | KMT2A (0.42) | ALDH1A1MAPK1MTNR1ACYP2C9CYP2C19 | |
| SCHEMBL16585774 | 0.66 | LMNA (0.47) | ALDH1A1L3MBTL1SLC6A3KMT2ATSHR | |
| SCHEMBL11203745 | 0.66 | GLA (0.59) | GLAALDH1A1MAPK1L3MBTL1SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL9037494 | 0.66 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7591575 | 0.65 | ITGB3 (0.46) | ALDH1A1MAPK1L3MBTL1SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046906-B1 | ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-08-16 | — | — | EP | disclosed |