Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265651 | 0.86 | GRM6 (0.41) | MAPTMEN1KMT2AADORA3ALDH1A1 | |
| SCHEMBL19265635 | 0.84 | ADORA3 (0.37) | MAPTADORA3ALDH1A1TRPV1TLR8 | |
| SCHEMBL19265647 | 0.79 | PRKCZ (0.37) | PRKCZDHFRMEN1KMT2AADORA3 | |
| SCHEMBL19265548 | 0.77 | LMNA (0.36) | MAPTTP53GAAMEN1KMT2A | |
| SCHEMBL10325968 | 0.76 | TLR8 (0.52) | PRKCZTLR8TLR7 | |
| SCHEMBL19265538 | 0.75 | MEN1 (0.40) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL19265659 | 0.73 | TLR8 (0.44) | MEN1KMT2AALDH1A1TLR8TLR7 | |
| SCHEMBL10325132 | 0.72 | TLR8 (0.37) | PRKCZMAPTTP53GAATLR8 | |
| SCHEMBL19265650 | 0.70 | KDM4E (0.39) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL19265541 | 0.68 | PPARA (0.33) | MAPTGAAADORA3ALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |