Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 20/20 | 1.00 |
| ▸ | ADAMTS13 | Q76LX8 | 2/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428710 | 0.67 | L3MBTL1 (0.50) | ADAMTS5 | |
| SCHEMBL16735375 | 0.63 | ADAMTS5 (0.59) | ADAMTS5ADAMTS13ADAMTS4MMP14 | |
| SCHEMBL7781288 | 0.60 | ADAMTS5 (0.43) | ADAMTS5 | |
| SCHEMBL13323 | 0.60 | ALDH1A1 (0.60) | — | |
| SCHEMBL9094523 | 0.59 | ADAMTS5 (0.42) | ADAMTS5 | |
| Hydrochloric Acid SCHEMBL30648399 | 0.59 | ALDH1A1 (0.58) | — | |
| SCHEMBL10610934 | 0.58 | ADAMTS5 (0.40) | ADAMTS5 | |
| SCHEMBL5834274 | 0.58 | KDR (0.41) | ADAMTS5 | |
| SCHEMBL2477193 | 0.57 | KDR (0.40) | ADAMTS5 | |
| SCHEMBL69404 | 0.57 | HPGD (0.48) | ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009903-A1 | MODULATING ADIPOSE TISSUE AND ADIPOGENESIS | KATHOLIEKE UNIV LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT (BE) | 2018-01-11 | — | — | US | disclosed |
| EP-3209794-A1 | MODULATING ADIPOSE TISSUE AND ADIPOGENESIS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2017-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009903-A1 | MODULATING ADIPOSE TISSUE AND ADIPOGENESIS | ADAMTS5, ADAMTS1, ADAMTS7 | ADAMTS5 1/4885ADAMTS13 9/4885ADAM17 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.