Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TTPA | P49638 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247633 | 1.00 | PTGS1 (0.78) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8270579 | 1.00 | PTGS1 (0.78) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL16369360 | 0.89 | PTGS1 (0.60) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| (R)-Trolox SCHEMBL615168 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL4647438 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL29375939 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL3226 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL1927837 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL1651402 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Trolox SCHEMBL29653919 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713564-B1 | COMPOUNDS AS MPGES-1 INHIBITORS | KHONDRION IP B V (NL) | 2023-11-15 | — | — | EP | disclosed |
| US-20230323250-A1 | FABRIC TREATMENT COMPOSITIONS WITH ANTIOXIDANT MULTIMERS | THE PROCTER & GAMBLE COMPANY | 2023-10-12 | — | — | US | disclosed |
| WO-2023196452-A1 | FABRIC TREATMENT COMPOSITIONS WITH ANTIOXIDANT MULTIMERS | THE PROCTER & GAMBLE COMPANY (US) | 2023-10-12 | — | — | WO | disclosed |
| US-11761953-B2 | Mediation of in vivo analyte signal degradation | SENSEONICS, INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-4241842-A2 | NOVEL TREATMENT OF MITOCHONDRIAL DISEASES | KHONDRION IP B.V. (NL) | 2023-09-13 | — | — | EP | disclosed |
| EP-3606522-B1 | NOVEL TREATMENT OF MITOCHONDRIAL DISEASES | KHONDRION IP B V (NL) | 2023-07-12 | — | — | EP | disclosed |
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |
| WO-2022093189-A1 | COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS | MILLIKEN & COMPANY (US) | 2022-05-05 | — | — | WO | disclosed |
| US-11136535-B2 | Leuco colorants as bluing agents in laundry care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200308220-A1 | AROMATIC-CATIONIC PEPTIDES CONJUGATED TO ANTIOXIDANTS AND THEIR USE IN TREATING COMPLEX REGIONAL PAIN SYNDROME | CLINICAL RESEARCH INSTITUTE OF MONTREAL (CA) | 2020-10-01 | — | — | US | disclosed |
| US-20070054900-A1 | 4-Phenlthiazole and 4-phenylimidizole derivatives and their use as medicaments for the treatment of neurodegenerative diseases, pain and epilepsy | SOCIETE DE CONSEILS DE RECHERCHES ET (FR) | 2007-03-08 | — | — | US | disclosed |
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SCRAS | 2007-01-25 | — | — | US | disclosed |
| EP-1675836-A1 | DERIVATIVES OF 4-PHENYLTHIAZOLES AND 4-PHENYLIMIDAZOLES AND THE USE THEREOF AS MEDICAMENTS FOR TREATING NEURODEGENERATIVE DISEASES, PAIN AND EPILEPSY | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2006-07-05 | — | — | EP | disclosed |
| EP-1589007-A2 | 5-membered heterocycle derivatives, production thereof and their use as medicaments | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005035510-A1 | DERIVATIVES OF 4-PHENYLTHIAZOLES AND 4-PHENYLIMIDAZOLES AND THE USE THEREOF AS MEDICAMENTS FOR TREATING NEURODEGENERATIVE DISEASES, PAIN AND EPILEPSY | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-04-21 | — | — | WO | disclosed |
| US-20050038087-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | IPSEN PHARMA S.A.S. (FR) | 2005-02-17 | — | — | US | disclosed |
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-08 | — | — | US | disclosed |
| EP-1228760-A2 | 5-membered heterocycle derivatives, production thereof and use thereof as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-08-07 | — | — | EP | disclosed |
| EP-1223933-A2 | 5-MEMBERED HETEROCYCLE DERIVATIVES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001026656-A2 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND USE THEREOF AS MONOAMINE OXIDASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | PARK7, SNCA, COMT | PTGS1 268/4885PTGS2 288/4885CYP1A2 298/4885 |
| US-20050038087-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | OXER1, OPRL1, OPRK1 | PTGS1 263/4885PTGS2 364/4885CYP1A2 173/4885 |
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | OPRK1, HCN1, P2RX7 | PTGS1 138/4885PTGS2 366/4885CYP1A2 143/4885 |
| US-20200308220-A1 | AROMATIC-CATIONIC PEPTIDES CONJUGATED TO ANTIOXIDANTS AND THEIR USE IN TREATING COMPLEX REGIONAL PAIN SYNDROME | QDPR, TYR, MTPN | PTGS1 2488/4885PTGS2 1677/4885CYP1A2 3422/4885 |
| US-20070054900-A1 | 4-Phenlthiazole and 4-phenylimidizole derivatives and their use as medicaments for the treatment of neurodegenerative diseases, pain and epilepsy | TPMT, P2RX4, CACNA1I | PTGS1 159/4885PTGS2 191/4885CYP1A2 545/4885 |
| US-11761953-B2 | Mediation of in vivo analyte signal degradation | SLC2A1, SLC2A8, SLC2A4 | PTGS1 1005/4885PTGS2 1474/4885CYP1A2 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.