Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | VIPR2 | P41587 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286187 | 0.78 | MEN1 (0.42) | MEN1ALDH1A1KMT2APSEN1PSEN2 | |
| SCHEMBL19286247 | 0.77 | ALPL (0.42) | MEN1KMT2A | |
| SCHEMBL19286314 | 0.77 | ALPL (0.42) | MEN1KMT2A | |
| SCHEMBL19286267 | 0.76 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL17470024 | 0.72 | MEN1 (0.41) | MEN1ALDH1A1KMT2APSEN1PSEN2 | |
| SCHEMBL19286276 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL19286217 | 0.71 | LTC4S (0.44) | — | |
| SCHEMBL19286193 | 0.70 | MAPT (0.48) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19286197 | 0.70 | MAPT (0.48) | MEN1ALDH1A1KMT2A | |
| SCHEMBL17470123 | 0.69 | MEN1 (0.41) | MEN1ALDH1A1KMT2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |