SCHEMBL19286276

SCHEMBL19286276

C[C@@H](NC(=S)N[C@@H](c1ccccc1)[C@H](c1ccccc1)N(C)C)[C@@H]1CCCC1(C)P(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19286247 0.84 ALPL (0.42) LMNAHPGDL3MBTL1
SCHEMBL19286314 0.84 ALPL (0.42) LMNAHPGDL3MBTL1
SCHEMBL19286216 0.80 KAT2B (0.30) NR3C1
SCHEMBL19286286 0.76 RECQL (0.32)
SCHEMBL19286217 0.74 LTC4S (0.44) LMNA
SCHEMBL19286303 0.74 ACHE (0.33) L3MBTL1
SCHEMBL19286267 0.73 ALDH1A1 (0.33) LMNAL3MBTL1
SCHEMBL19286279 0.73 L3MBTL1 (0.32) L3MBTL1
SCHEMBL19286197 0.72 MAPT (0.48) LMNA
SCHEMBL19286193 0.72 MAPT (0.48) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9744528-B2 Metallorganocatalysis for asymmetric transformations RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-08-29 US disclosed