Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286300 | 0.86 | KDM4E (0.42) | EPHX2GAAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL19286193 | 0.74 | MAPT (0.48) | EPHX2GAASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19286197 | 0.74 | MAPT (0.48) | EPHX2GAASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19286314 | 0.70 | ALPL (0.42) | GAAL3MBTL1TDP1LMNANPC1 | |
| SCHEMBL19286247 | 0.70 | ALPL (0.42) | GAAL3MBTL1TDP1LMNANPC1 | |
| SCHEMBL19286267 | 0.70 | ALDH1A1 (0.33) | L3MBTL1SMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL19286232 | 0.68 | TRPA1 (0.33) | L3MBTL1 | |
| SCHEMBL19286245 | 0.68 | TRPA1 (0.33) | L3MBTL1 | |
| SCHEMBL19286316 | 0.67 | NR3C1 (0.33) | L3MBTL1 | |
| SCHEMBL19286303 | 0.66 | ACHE (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |