Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13131104 | 0.87 | CTRB1 (0.37) | DDB1CRBNSLC6A2SLC6A3CTRC | |
| SCHEMBL13131053 | 0.86 | DDB1 (0.34) | DDB1CRBNSLC6A2SLC6A3CTRC | |
| SCHEMBL13130988 | 0.86 | DDB1 (0.34) | DDB1CRBNSLC6A2SLC6A3CTRC | |
| SCHEMBL4567673 | 0.82 | HPGD (0.37) | ALDH1A1ALDH2HPGD | |
| SCHEMBL13131098 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL13130998 | 0.76 | — | — | |
| SCHEMBL13130992 | 0.75 | HPGD (0.33) | ALDH1A1ALDH2HPGD | |
| SCHEMBL1930872 | 0.74 | PSEN1 (0.41) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL28660105 | 0.74 | PSEN1 (0.41) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL13131164 | 0.73 | ACHE (0.31) | DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8506945-B2 | Polymers with structure-defined functions | SMITH & NEPHEW, PLC. (GB) | 2013-08-13 | — | — | US | disclosed |
| US-20110300096-A1 | Polymers With Structure-Defined Functions | GREENER BRYAN (GB) | 2011-12-08 | — | — | US | disclosed |
| US-7955594-B2 | Maleic anhydride-methyl vinyl ether copolymers; polyamic acids; medical implant device, dressing, scaffold, or fluid adhesive for treatment or prophylaxis of wounds; enhanced activity of protease inhibitors and neurotransmitter drugs | SMITH & NEPHEW, PLC (GB) | 2011-06-07 | — | — | US | disclosed |
| US-20050032929-A1 | Polymers with structure-defined functions | SMITH & NEPHEW, PLC (GB) | 2005-02-10 | — | — | US | disclosed |
| EP-1436334-A1 | POLYMERS WITH STRUCTURE-DEFINED FUNCTIONS | Smith & Nephew PLC (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003027154-A1 | POLYMERS WITH STRUCTURE-DEFINED FUNCTIONS | SMITH & NEPHEW PLC (GB) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110300096-A1 | Polymers With Structure-Defined Functions | MMP1, MMP8, ADAM12 | DDB1 2927/4885CRBN 2978/4885SLC6A2 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.