Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL4138391 | 0.92 | THRB (0.36) | THRBTSHRGLO1ALDH1A1NPSR1 | |
| Methacrylic Acid SCHEMBL27790083 | 0.89 | THRB (0.47) | THRBTSHRGLO1ALDH1A1NPSR1 | |
| SCHEMBL4810104 | 0.85 | THRB (0.53) | THRBTSHRGLO1ALDH1A1NPSR1 | |
| Acrylic Acid SCHEMBL28568730 | 0.79 | ALDH1A1 (0.44) | THRBTSHRGLO1ALDH1A1CYP2D6 | |
| SCHEMBL27832581 | 0.78 | ALDH1A1 (0.56) | THRBTSHRGLO1ALDH1A1CYP2D6 | |
| SCHEMBL28342228 | 0.78 | ALDH1A1 (0.56) | THRBTSHRGLO1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL4131844 | 0.78 | CHRM5 (0.49) | THRBTSHRCYP2D6CYP2C19LMNA | |
| Methacrylic Acid SCHEMBL15456814 | 0.77 | THRB (0.53) | THRBTSHRGLO1ALDH1A1NPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL13519363 | 0.77 | THRB (0.39) | THRBTSHRALDH1A1CYP2D6CYP2C19 | |
| Methylene Chloride SCHEMBL28244287 | 0.77 | THRB (0.57) | THRBTSHRGLO1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040527-A1 | DOPA FORMULATIONS FOR TREATMENTS OF PARKINSON'S DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-02-28 | — | — | WO | disclosed |
| US-20190054051-A1 | DOPA Formulations for Treatments of Parkinson's Disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-02-21 | — | — | US | disclosed |
| US-20130059003-A1 | SUSTAINED RELEASE DONEPEZIL FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| WO-2011069076-A2 | SUSTAINED RELEASE DONEPEZIL FORMULATIONS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190054051-A1 | DOPA Formulations for Treatments of Parkinson's Disease | PARK7, SLC6A3, SNCA | THRB 3292/4885TSHR 1911/4885GLO1 719/4885 |
| US-20130059003-A1 | SUSTAINED RELEASE DONEPEZIL FORMULATIONS | ACHE, SLC6A2, BCHE | THRB 1623/4885TSHR 1795/4885GLO1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.