SCHEMBL193399

SCHEMBL193399

CCCC1NC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 1/20 0.44
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.37
ADAMTS5 Q9UNA0 8/20 0.37
ADAMTS4 O75173 2/20 0.37
ADAM10 O14672 1/20 0.36
MMP12 P39900 1/20 0.36
ADAM17 P78536 1/20 0.36
ADAM9 Q13443 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15014722 1.00 SMN1; SMN2 (0.50) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL194066 0.87 ALDH1A1 (0.50) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL17830363 0.87 ALDH1A1 (0.50) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL18165385 0.87 ALDH1A1 (0.50) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL896587 0.85 ALDH1A1 (0.44) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL10446067 0.84 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL9402138 0.84 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL9136883 0.84 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL9402128 0.84 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
SCHEMBL10407687 0.84 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118398588-B Gold-silver alloy structure for semiconductor device and preparation method thereof 深圳市联合蓝海应用材料科技股份有限公司 2024-11-15 CN claimed
CN-118853788-A Preparation method of L-norvaline 河北利仕化学科技有限公司 2024-10-29 CN claimed
CN-118398588-A Gold-silver alloy structure for semiconductor device and preparation method thereof 深圳市联合蓝海应用材料科技股份有限公司 2024-07-26 CN claimed
CN-116715635-A Synthesis process of 5-n-propyl hydantoin 河北鑫淘沅医药科技有限公司 2023-09-08 CN claimed
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
EP-2988830-B1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF OREAL (FR) 2021-03-17 EP claimed
EP-2916808-B1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION OREAL (FR) 2019-06-26 EP claimed
US-20190167552-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR L'OREAL (FR) 2019-06-06 US claimed
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER L'OREAL (FR) 2019-04-25 US claimed
EP-2988830-A2 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF L'Oréal (FR) 2016-03-02 EP claimed
US-20150305999-A1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION L'OREAL (FR) 2015-10-29 US claimed
EP-2916808-A1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION L'Oréal (FR) 2015-09-16 EP claimed
WO-2014174075-A2 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF L'OREAL (FR) 2014-10-30 WO claimed
WO-2014072658-A1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION L'OREAL (FR) 2014-05-15 WO claimed
US-20100284954-A1 PROCESS FOR RELAXING KERATIN FIBRES L'OREAL (FR) 2010-11-11 US claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
US-4107153-A Heat-resistant thermosetting polyimide resin TOSHIBA CHEMICAL PRODUCTS CO., LTD. (JP) 1978-08-15 US claimed
US-4097545-A Heat-resistant thermosetting polyimide resin with bis-phenol-epichlorohydrin reaction product TOSHIBA CHEMICAL PRODUCTS CO. LTD. (JA) 1978-06-27 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100284954-A1 PROCESS FOR RELAXING KERATIN FIBRES KRT18, TPM4, MYLK SMN1; SMN2 3501/4885TSHR 3657/4885ALDH1A1 4398/4885
US-20190167552-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR KRT18, OAT, CKMT1A; CKMT1B SMN1; SMN2 4548/4885TSHR 4719/4885ALDH1A1 2800/4885
US-11298305-B2 Compositions and methods for improving the appearance of the hair KRT18, OAT, CKMT1A; CKMT1B SMN1; SMN2 4548/4885TSHR 4719/4885ALDH1A1 2800/4885
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER KRT18, CUTA, MARK1 SMN1; SMN2 4265/4885TSHR 4385/4885ALDH1A1 2616/4885
US-20150305999-A1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION KRT18, MAPT, CUTA SMN1; SMN2 4377/4885TSHR 3058/4885ALDH1A1 1126/4885
US-20060127337-A1 Process for relaxing keratin fibres KRT18, TPM4, MYLK SMN1; SMN2 3501/4885TSHR 3657/4885ALDH1A1 4398/4885
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone KRT18, CUTA, PUF60 SMN1; SMN2 4493/4885TSHR 4539/4885ALDH1A1 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.