Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935304 | 0.92 | TEK (0.39) | MAT2AEIF4ETEKCDC7ROS1 | |
| SCHEMBL1935549 | 0.85 | ALOX5AP (0.40) | AKR1C3AKR1C2EIF4EPDE3BPDE3A | |
| SCHEMBL2218335 | 0.85 | TRPA1 (0.43) | EIF4EPDE3BPDE3ATGFBR1 | |
| SCHEMBL2218705 | 0.84 | KDM4C (0.38) | AKR1C3AKR1C2PDE3BPDE3AROS1 | |
| SCHEMBL1935091 | 0.82 | TGFBR1 (0.47) | AKR1C3TGFBR1 | |
| SCHEMBL1935554 | 0.81 | ALDH1A1 (0.40) | AKR1C3AKR1C2MAT2AEIF4EPDE3B | |
| SCHEMBL1935744 | 0.78 | TRPA1 (0.43) | PDE3BPDE3AROS1MAPKAPK2TGFBR1 | |
| SCHEMBL1934823 | 0.78 | JAK2 (0.39) | MAPKAPK2TGFBR1CBFB | |
| SCHEMBL2220256 | 0.78 | TGFBR1 (0.40) | PDE3BPDE3ATGFBR1 | |
| SCHEMBL1934736 | 0.76 | KMO (0.46) | PDE3BPDE3AMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332936-B1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2332936-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | AKR1C3 475/4885AKR1C2 1383/4885MAT2A 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.