SCHEMBL1936346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28433847	0.82	KMT2A (0.46)	ALDH1A1MAPTLMNA
	SCHEMBL28669741	0.81	ALDH1A1 (0.64)	KMOERN1TP53CASP6PTGER1
	SCHEMBL20189898	0.81	ALDH1A1 (0.61)	ALDH1A1MAPT
	SCHEMBL29973546	0.81	ALDH1A1 (0.61)	ALDH1A1MAPT
	SCHEMBL1936226	0.81	ROCK2 (0.52)	ALDH1A1ROCK2MAPT
	SCHEMBL1018931	0.77	KMO (0.60)	KMODDTPTGER1CYP3A4CYP2C9
	SCHEMBL26969164	0.77	PTAFR (0.47)	ERN1CYP3A4CYP2C9ALDH1A1ROCK2
	SCHEMBL408308	0.76	ERN1 (0.59)	KMOERN1TP53CASP6ALDH1A1
	SCHEMBL31415060	0.76	ERN1 (0.59)	KMOERN1TP53CASP6ALDH1A1
	SCHEMBL17461846	0.76	CASP6 (0.53)	ERN1TP53CASP6ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.