Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365410 | 1.00 | RAB9A (0.41) | RAB9AMEN1KMT2ANPC1CNR2 | |
| SCHEMBL19365401 | 0.93 | MALT1 (0.40) | RAB9ACNR2GSK3BDYRK1ABTK | |
| SCHEMBL19365400 | 0.93 | MALT1 (0.40) | RAB9ACNR2GSK3BDYRK1ABTK | |
| SCHEMBL19365560 | 0.90 | CNR2 (0.42) | RAB9AMEN1KMT2ANPC1CNR2 | |
| SCHEMBL19365553 | 0.90 | CNR2 (0.42) | RAB9AMEN1KMT2ANPC1CNR2 | |
| SCHEMBL19670235 | 0.88 | GSK3B (0.36) | RAB9AMEN1KMT2AGSK3BDYRK1A | |
| SCHEMBL19364826 | 0.86 | FAAH (0.42) | RAB9AMEN1KMT2ANPC1GSK3B | |
| SCHEMBL19670319 | 0.86 | FAAH (0.42) | RAB9AMEN1KMT2ANPC1GSK3B | |
| SCHEMBL19365770 | 0.86 | ALDH1A1 (0.38) | RAB9AMEN1KMT2ANPC1CNR2 | |
| SCHEMBL19670222 | 0.86 | ALDH1A1 (0.38) | RAB9AMEN1KMT2ANPC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |