SCHEMBL19429565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27964383	0.82	SIRT6 (0.62)	SIRT6APLNRNNMTOXTRMEN1
	SCHEMBL21778758	0.79	CNR2 (0.37)	SIRT6BACE1
	SCHEMBL21778743	0.78	SIRT6 (0.49)	SIRT6KMT2AMAPTKDM4ENPC1
	SCHEMBL15751614	0.77	SIRT6 (0.61)	SIRT6APLNRNNMTMEN1KMT2A
	SCHEMBL14684026	0.77	SIRT6 (0.61)	SIRT6APLNRNNMTOXTRMEN1
	SCHEMBL27635499	0.72	SIRT6 (0.59)	SIRT6MEN1KMT2AMAPTKDM4E
	SCHEMBL347508	0.72	SIRT6 (0.75)	SIRT6APLNRNNMTMAPTKDM4E
	SCHEMBL14113834	0.72	SIRT6 (0.69)	SIRT6APLNRNNMTOXTRMEN1
	SCHEMBL31132573	0.72	SIRT6 (0.75)	SIRT6APLNRNNMTMAPTKDM4E
	SCHEMBL23369518	0.71	LMNA (0.37)	MEN1KMT2AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.