SCHEMBL194433

SCHEMBL194433

CN(C)c1ccc2c(C(F)(F)F)cc(=O)oc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.70
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
CASP1 P29466 2/20 0.61
CASP7 P55210 2/20 0.61
ATM Q13315 2/20 0.61
HSD17B10 Q99714 2/20 0.61
HSD17B3 P37058 1/20 0.61
KDM4E B2RXH2 1/20 0.61
MEN1 O00255 1/20 0.61
GAA P10253 1/20 0.61
SRC P12931 1/20 0.61
KMT2A Q03164 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
TLR9 Q9NR96 1/20 0.61
MAP2K1 Q02750 1/20 0.56
MCL1 Q07820 1/20 0.53
AGER Q15109 2/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30275399 1.00 AR (0.70) ARALDH1A1HPGDCASP1CASP7
SCHEMBL10086178 0.88 AR (0.55) ARALDH1A1HPGDCASP1CASP7
Coumarin SCHEMBL6849968 0.88 AR (0.56) ARALDH1A1HPGDCASP1CASP7
SCHEMBL29551746 0.85 AR (0.75) ARALDH1A1HPGDCASP1CASP7
SCHEMBL144250 0.85 AR (0.75) ARALDH1A1HPGDCASP1CASP7
SCHEMBL24803039 0.85 AR (0.67) ARALDH1A1HPGDCASP1CASP7
SCHEMBL31331897 0.85 AR (0.62) ARALDH1A1HPGDCASP1CASP7
SCHEMBL10086176 0.81 CYP1A2 (0.53) ARALDH1A1HPGDCASP1CASP7
SCHEMBL3626007 0.80 ALDH1A1 (0.80) ARALDH1A1HPGDCASP1CASP7
SCHEMBL31331847 0.80 AR (0.59) ARALDH1A1HPGDCASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230201624-A1 NON-INVASIVE ENERGY UPCONVERSION METHODS AND SYSTEMS FOR IN-SITU PHOTOBIOMODULATION IMMUNOLIGHT, LLC (US) 2023-06-29 US claimed
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-10493296-B2 Non-invasive energy upconversion methods and systems for in-situ photobiomodulation IMMUNOLIGHT, LLC (US) 2019-12-03 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
US-20170096545-A1 SOLID STATE DYE LASER AND METHODS FOR PREPARING THE SAME KING ABDULAZIZ CITY SCIENCE & TECHNOLOGY (KACST) (SA) 2017-04-06 US claimed
US-20170000908-A1 A MICELLAR PARTICLE NATIONAL UNIVERSITY OF SINGAPORE (SG) 2017-01-05 US claimed
US-9526913-B2 Non-invasive energy upconversion methods and systems DUKE UNIVERSITY (US) 2016-12-27 US claimed
US-5829448-A ANTITUMOR PHOTOGEN, INC. (US) 1998-11-03 US claimed
US-5807605-A Lubricant soluble fluorescent agent and method for its use in a system for detection of lubricant coatings BECTON DICKINSON AND COMPANY (US) 1998-09-15 US claimed
WO-1998018398-A1 METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS PHOTOGEN, INC. (US) 1998-05-07 WO claimed
WO-1998018399-A1 METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION OF MOLECULAR AGENTS PHOTOGEN, INC. (US) 1998-05-07 WO claimed
US-5667840-A Lubricant soluble fluorescent agent and method for its use in a system for detection of lubricant coatings BECTON DICKINSON AND COMPANY 1997-09-16 US claimed
EP-0793089-A2 Lubricant-soluble fluorescent agent and method for its use in a system for detecting lubricant coatings Becton, Dickinson and Company (US) 1997-09-03 EP claimed
US-5610932-A Solid state dye laser host PHYSICAL SCIENCES, INC. (US) 1997-03-11 US claimed
EP-0431452-B1 Method for the optical distinction of dental materials and material used in this method IVOCLAR AG (LI) 1994-10-05 EP claimed
US-5102461-A PROCESS FOR THE OPTICAL DISTINCTION OF A DENTAL MATERIAL AND DENTAL MATERIAL FOR SAID PROCESS IVOCLAR AG (DE) 1992-04-07 US claimed
EP-0431452-A2 Method for the optical distinction of dental materials and material used in this method IVOCLAR AG (LI) 1991-06-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10493296-B2 Non-invasive energy upconversion methods and systems for in-situ photobiomodulation MAVS, NLN, FURIN AR 4694/4885ALDH1A1 3589/4885HPGD 3470/4885
US-20170000908-A1 A MICELLAR PARTICLE CHMP4B, NPC1L1, CAPG AR 1571/4885ALDH1A1 2143/4885HPGD 4520/4885
US-20230201624-A1 NON-INVASIVE ENERGY UPCONVERSION METHODS AND SYSTEMS FOR IN-SITU PHOTOBIOMODULATION MAVS, NLN, FURIN AR 4694/4885ALDH1A1 3589/4885HPGD 3470/4885
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX AR 2694/4885ALDH1A1 262/4885HPGD 237/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH AR 2416/4885ALDH1A1 179/4885HPGD 704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.