Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167957 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2D6CYP1A2PTPN1 | |
| SCHEMBL12356881 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2D6CYP1A2PTPN1 | |
| SCHEMBL17885861 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2D6CYP1A2PTPN1 | |
| SCHEMBL10419000 | 0.76 | TSHR (0.52) | ALDH1A1TSHRCYP1A2PTPN1KCNN4 | |
| SCHEMBL5872368 | 0.73 | KCNN4 (0.40) | ALDH1A1TSHRCYP2D6CYP1A2PTPN1 | |
| SCHEMBL22402881 | 0.72 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6CYP1A2KCNN4 | |
| SCHEMBL11044685 | 0.72 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6CYP1A2KCNN4 | |
| SCHEMBL3079554 | 0.72 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6CYP1A2KCNN4 | |
| SCHEMBL5872364 | 0.72 | HTR2A (0.40) | ALDH1A1TSHRCYP2D6CYP1A2MAPK1 | |
| SCHEMBL24342382 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2D6CYP1A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | ALDH1A1 1350/4885TSHR 3436/4885CYP2D6 61/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | ALDH1A1 1160/4885TSHR 3280/4885CYP2D6 55/4885 |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | ALDH1A1 1350/4885TSHR 3436/4885CYP2D6 61/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | ALDH1A1 1350/4885TSHR 3436/4885CYP2D6 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.