Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HBB | P68871 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244947 | 0.90 | MAPT (0.50) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8981580 | 0.80 | SMN1; SMN2 (0.42) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19487203 | 0.77 | MMP1 (0.41) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21401818 | 0.75 | SMN1; SMN2 (0.39) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11245003 | 0.72 | KLK5 (0.34) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4271408 | 0.72 | L3MBTL1 (0.41) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11702489 | 0.72 | RAB9A (0.37) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7535852 | 0.72 | LMNA (0.38) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16641019 | 0.71 | HPGD (0.51) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL932900 | 0.71 | HPGD (0.51) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796927-B2 | Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same | JNC CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |