Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR known ✓ | P00374 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | HNF4A | P41235 | 3/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7131147 | 0.98 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 | |
| Water SCHEMBL17259196 | 0.98 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 | |
| SCHEMBL9813477 | 0.96 | PTPN1 (0.51) | PTPN1HNF4AACMSDDHFRMCL1 | |
| SCHEMBL29478249 | 0.96 | PTPN1 (0.50) | PTPN1HNF4AACMSDDHFRMCL1 | |
| Benzene SCHEMBL3625753 | 0.96 | PTPN1 (0.50) | PTPN1HNF4AACMSDDHFRMCL1 | |
| SCHEMBL49835 | 0.96 | PTPN1 (0.50) | PTPN1HNF4AACMSDDHFRMCL1 | |
| SCHEMBL29404854 | 0.94 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 | |
| Hydrochloric Acid SCHEMBL15549923 | 0.94 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 | |
| Methane SCHEMBL29177518 | 0.94 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 | |
| SCHEMBL8804751 | 0.94 | PTPN1 (0.49) | PTPN1HNF4AACMSDDHFRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005015309-A2 | ALKALI-DEVELOPABLE RADIATION CURABLE COMPOSITION | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2005-02-17 | — | — | WO | claimed |
| JP-7094533-A | — | — | None | — | — | JP | disclosed |
| JP-7003018-A | — | — | None | — | — | JP | disclosed |
| JP-7094502-A | — | — | None | — | — | JP | disclosed |
| CN-110402511-B | Binder composition for secondary battery | 日本电气株式会社 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023157732-A1 | POLYAMIDIMIDE RESIN, POLYAMIDIMIDE FIBERS, NON-WOVEN FABRIC AND ELECTRONIC COMPONENT SEPARATOR | 東洋紡株式会社 | 2023-08-24 | — | — | WO | disclosed |
| CN-109388024-B | Photosensitive resin composition and method for producing the same, black matrix, pixel layer, protective film, color filter, and liquid crystal display device | 奇美实业股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115113481-A | Photosensitive resin, photosensitive resin composition, cured product, and color filter | 日铁化学材料株式会社 | 2022-09-27 | — | — | CN | disclosed |
| CN-113934112-A | Protective film, photosensitive resin composition and display device | 日铁化学材料株式会社 | 2022-01-14 | — | — | CN | disclosed |
| US-11209734-B2 | Oxime ester photoinitiators | BASF SE | 2021-12-28 | — | — | US | disclosed |
| EP-0646845-A1 | COLOR FILTER, MATERIAL THEREOF AND RESIN | Nippon Steel Corporation (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0393638-B1 | Thermosetting resin compostion and thermosetting dry film | UBE INDUSTRIES (JP) | 1995-01-11 | — | — | EP | disclosed |
| JP-H073018-A | POLYIMIDE RESIN | TOSHIBA CHEM CORP | 1995-01-06 | — | — | JP | disclosed |
| EP-0390992-B1 | Aromatic polyimide double layered hollow filamentary membrane and process for producing same | UBE INDUSTRIES (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5286539-A | HOMOGENEOUS AND POROUS LAYERS OF AROMATIC POLYIMIDES HAVING SPECIFIED STRUCTURES | UBE INDUSTRIES, LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| US-5246743-A | Biphenyltetracarboxylic acids and hexafluoroisopropylidene biphenyltetracarboxylic acid | UBE INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5141642-A | Separators for reverse osmosis, ultrafiltration, dehydration, heat and chemical resistance, strength, gas permeability | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5128444-A | Heat resistant adhesive | UBE INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0446947-A2 | Gas separating asymmetric membrane | UBE INDUSTRIES, LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0390992-A1 | Aromatic polyimide double layered hollow filamentary membrane and process for producing same | UBE INDUSTRIES, LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11209734-B2 | Oxime ester photoinitiators | OR10J3, OXER1, QSOX1 | DHFR 366/4885PTPN1 1422/4885HNF4A 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.