Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PPP5C | P53041 | 1/20 | 0.42 |
| ▸ | TKT | P29401 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387753 | 0.86 | HSP90AA1 (0.44) | HSP90AA1PPP5CTKTTDP1LMNA | |
| SCHEMBL19598908 | 0.74 | PPP5C (0.50) | HSP90AA1PPP5CTKTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL2949884 | 0.72 | TKT (0.69) | HSP90AA1PPP5CTKTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL5940670 | 0.69 | HSP90AA1 (0.57) | HSP90AA1PPP5CTKTTDP1LMNA | |
| SCHEMBL13741845 | 0.69 | TKT (0.71) | HSP90AA1PPP5CTKTTDP1KDM4E | |
| Thiamine Ion SCHEMBL16685322 | 0.68 | HSP90AA1 (0.71) | HSP90AA1TKTTDP1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL4355811 | 0.68 | TKT (0.70) | HSP90AA1PPP5CTKTTDP1KDM4E | |
| Thiamine Ion SCHEMBL29232851 | 0.67 | HSP90AA1 (0.85) | HSP90AA1TKTTDP1LMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6831590 | 0.66 | HSP90AA1 (0.69) | HSP90AA1TKTTDP1LMNAALDH1A1 | |
| Thiamine Ion SCHEMBL5329756 | 0.66 | HSP90AA1 (0.69) | HSP90AA1TKTTDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327449-A1 | NOVEL PROCESS FOR PREPARING SYNTHESIS INTERMEDIATES USING PRODUCTS OF NATURAL ORIGIN AND USE OF THE INTERMEDIATES OBTAINED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327449-A1 | NOVEL PROCESS FOR PREPARING SYNTHESIS INTERMEDIATES USING PRODUCTS OF NATURAL ORIGIN AND USE OF THE INTERMEDIATES OBTAINED | ADH7, ADH1B, ADH4 | HSP90AA1 1258/4885PPP5C 2421/4885TKT 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.