Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19600777 | 0.78 | AR (0.49) | AR | |
| SCHEMBL22527193 | 0.74 | AR (0.34) | ARCA2 | |
| SCHEMBL13336066 | 0.73 | CYP3A4 (0.40) | ARCA2 | |
| SCHEMBL20821916 | 0.72 | AR (0.33) | AR | |
| SCHEMBL32659686 | 0.71 | ALDH1A1 (0.46) | CA2 | |
| SCHEMBL10824246 | 0.71 | GABRA1 (0.37) | ARCA2 | |
| SCHEMBL16019379 | 0.68 | ALOX5AP (0.31) | ARCA2 | |
| SCHEMBL802989 | 0.68 | P2RX7 (0.53) | CA2 | |
| SCHEMBL19104073 | 0.68 | ALOX5AP (0.31) | ARCA2 | |
| SCHEMBL2199206 | 0.67 | CA2 (0.55) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327492-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327492-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | RORA, RORC, RORB | AR 757/4885PDE2A 3835/4885CA2 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.