Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622278 | 0.93 | OPRM1 (0.41) | PDE4BOPRM1OPRD1HRH3OPRK1 | |
| SCHEMBL19622279 | 0.74 | HRH3 (0.38) | PDE4BOPRM1OPRD1HRH3OPRK1 | |
| SCHEMBL19622337 | 0.71 | LMNA (0.50) | PDE4BOPRM1OPRD1OPRK1MAPT | |
| SCHEMBL19622338 | 0.70 | LMNA (0.49) | PDE4BOPRM1OPRD1OPRK1MAPT | |
| SCHEMBL19622328 | 0.69 | PDE4B (0.44) | PDE4BOPRM1OPRD1STSPDE4D | |
| SCHEMBL19622283 | 0.68 | MAPT (0.45) | OPRM1OPRD1HRH3OPRK1MAPT | |
| SCHEMBL19622334 | 0.68 | P2RX3 (0.41) | — | |
| SCHEMBL24376943 | 0.67 | KDM4E (0.56) | OPRM1OPRD1HRH3OPRK1MAPT | |
| SCHEMBL9607407 | 0.66 | HRH3 (0.58) | HRH3L3MBTL1 | |
| SCHEMBL19622288 | 0.66 | CYP4F2 (0.41) | PDE4BOPRM1OPRD1HRH3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |