Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19625008 | 0.87 | SLC9A1 (0.39) | SLC9A1KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL15506643 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL29063172 | 0.81 | SLC9A1 (0.41) | SLC9A1KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL19625090 | 0.78 | FLT3 (0.53) | SLC9A1KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL22620591 | 0.77 | KIF11 (0.43) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL25758852 | 0.74 | MEN1 (0.51) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL15506670 | 0.74 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL19624948 | 0.70 | HTR6 (0.39) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL3392115 | 0.70 | DAO (0.59) | KDM4EALDH1A1MAPT | |
| SCHEMBL28577661 | 0.70 | NR3C1 (0.41) | KDM4EALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892880-B1 | INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-22 | — | — | EP | disclosed |