Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963180 | 0.91 | CA12 (0.30) | — | |
| SCHEMBL9274041 | 0.86 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL1964741 | 0.84 | CYP1A2 (0.32) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL1965873 | 0.84 | HPD (0.37) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL12478106 | 0.82 | HPD (0.31) | — | |
| SCHEMBL1965659 | 0.81 | HPD (0.33) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL1965392 | 0.80 | KDM4E (0.35) | MAPTALDH1A1HTTSMN1; SMN2 | |
| Tembotrione SCHEMBL3762569 | 0.76 | HPD (0.31) | — | |
| SCHEMBL8848046 | 0.76 | ALDH1A1 (0.44) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL5604518 | 0.75 | ALDH1A1 (0.35) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| EP-2675277-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | Bayer Intellectual Property GmbH (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-28 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| WO-2012110517-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | WO | disclosed |
| WO-2008131860-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008131861-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| CN-1949966-A | Quinoxalin-2-one derivatives, crop protection agents comprising the same and method for production and use therof | BAYER CROPSCIENCE GMBH (DE) | 2007-04-18 | — | — | CN | disclosed |
| EP-1746880-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | Bayer CropScience GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112630-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | BAYER CROPSCIENCE GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | BAYER CROPSCIENCE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | CYP1A2 18/4885CYP3A4 118/4885CYP2D6 55/4885 |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | QSOX1, CYC1, CBR3 | CYP1A2 55/4885CYP3A4 298/4885CYP2D6 184/4885 |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | CYP1A2 74/4885CYP3A4 202/4885CYP2D6 763/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | CYP1A2 51/4885CYP3A4 116/4885CYP2D6 621/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | CYP1A2 220/4885CYP3A4 824/4885CYP2D6 1422/4885 |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | DDT, ING2, DNER | CYP1A2 1091/4885CYP3A4 2239/4885CYP2D6 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.