Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | BHMT | Q93088 | 4/20 | 0.46 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628285 | 1.00 | CYP2D6 (0.46) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| SCHEMBL19628287 | 1.00 | CYP2D6 (0.46) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| SCHEMBL14286756 | 0.84 | NOS2 (0.38) | BHMTNOS2NOS1NOS3ARG1 | |
| SCHEMBL24919549 | 0.84 | NOS2 (0.38) | BHMTNOS2NOS1NOS3ARG1 | |
| SCHEMBL22625614 | 0.84 | NOS2 (0.42) | BHMTNOS2NOS1NOS3ARG1 | |
| Carbocysteine SCHEMBL20854 | 0.82 | BHMT (0.59) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| Carbocysteine SCHEMBL6762355 | 0.82 | BHMT (0.59) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| Carbocysteine SCHEMBL9236855 | 0.82 | BHMT (0.59) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| Carbocysteine SCHEMBL69149 | 0.82 | BHMT (0.59) | CYP2D6HIF1ABHMTNOS2NOS1 | |
| SCHEMBL12660173 | 0.81 | CYP2C19 (0.50) | CYP2D6HIF1ABHMTNOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333374-A1 | S-(CARBOXYMETHYL)-CYSTEINE PHARMACEUTICAL COMPOUND AND PREPARATION METHOD AND USE THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD., BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333374-A1 | S-(CARBOXYMETHYL)-CYSTEINE PHARMACEUTICAL COMPOUND AND PREPARATION METHOD AND USE THEREOF | CBS, SRM, CTH | CYP2D6 1476/4885HIF1A 2698/4885BHMT 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.