Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634192 | 0.85 | APLNR (0.34) | APLNRQPCTALDH1A1LMNA | |
| SCHEMBL19634304 | 0.85 | ACLY (0.35) | APLNRQPCTALDH1A1LMNA | |
| SCHEMBL19634264 | 0.81 | GCK (0.33) | APLNRNPC1RAB9AALDH1A1 | |
| SCHEMBL19613502 | 0.78 | ACLY (0.37) | APLNRALDH1A1LMNANPSR1 | |
| SCHEMBL21783460 | 0.74 | ALDH1A1 (0.34) | APLNRTSPOALDH1A1LMNA | |
| SCHEMBL21794068 | 0.73 | APLNR (0.34) | APLNRALDH1A1LMNA | |
| SCHEMBL19634133 | 0.72 | HTR2A (0.38) | APLNRTDP1ALDH1A1LMNA | |
| SCHEMBL21117650 | 0.70 | ACLY (0.39) | APLNRERN1 | |
| SCHEMBL21794109 | 0.70 | ALDH1A1 (0.34) | APLNRTSPOALDH1A1LMNA | |
| SCHEMBL19634161 | 0.70 | ALDH1A1 (0.34) | APLNRTSPOQPCTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |