Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634192 | 0.91 | APLNR (0.34) | MEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL19634304 | 0.83 | ACLY (0.35) | MEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL19634076 | 0.81 | APLNR (0.32) | NPC1RAB9AAPLNRALDH1A1 | |
| SCHEMBL21794109 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL19634161 | 0.78 | ALDH1A1 (0.34) | MEN1NPC1RAB9AKMT2AAPLNR | |
| SCHEMBL19631521 | 0.77 | ACLY (0.36) | APLNRALDH1A1 | |
| SCHEMBL21783460 | 0.76 | ALDH1A1 (0.34) | MEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL21794068 | 0.73 | APLNR (0.34) | MEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL21793990 | 0.70 | ACLY (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19634133 | 0.70 | HTR2A (0.38) | MEN1KMT2AAPLNRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |