Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634264 | 0.91 | GCK (0.33) | APLNRMEN1ALDH1A1KMT2A | |
| SCHEMBL19634304 | 0.88 | ACLY (0.35) | APLNRQPCTLMNAMEN1ALDH1A1 | |
| SCHEMBL19634076 | 0.85 | APLNR (0.32) | APLNRQPCTLMNAALDH1A1 | |
| SCHEMBL21783460 | 0.76 | ALDH1A1 (0.34) | APLNRLMNAMEN1ALDH1A1CYP1A2 | |
| SCHEMBL19613710 | 0.76 | ACLY (0.38) | APLNRLMNAALDH1A1 | |
| SCHEMBL21794068 | 0.76 | APLNR (0.34) | APLNRLMNAMEN1ALDH1A1CYP1A2 | |
| SCHEMBL19634133 | 0.75 | HTR2A (0.38) | APLNRLMNAMEN1ALDH1A1CYP1A2 | |
| SCHEMBL21794109 | 0.74 | ALDH1A1 (0.34) | APLNRLMNAMEN1ALDH1A1CYP1A2 | |
| SCHEMBL19634161 | 0.74 | ALDH1A1 (0.34) | APLNRQPCTLMNAMEN1ALDH1A1 | |
| SCHEMBL21793990 | 0.71 | ACLY (0.35) | LMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |