Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21794109 | 0.85 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBSMN1; SMN2TSPO | |
| SCHEMBL19634264 | 0.78 | GCK (0.33) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19631718 | 0.76 | MMP9 (0.44) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21783460 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBSMN1; SMN2TSPO | |
| SCHEMBL19634192 | 0.74 | APLNR (0.34) | ALDH1A1QPCTLMNAMEN1KMT2A | |
| SCHEMBL21773016 | 0.72 | CNR2 (0.42) | ALDH1A1LMNAAPLNR | |
| SCHEMBL21794068 | 0.72 | APLNR (0.34) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19634304 | 0.72 | ACLY (0.35) | ALDH1A1QPCTLMNASMN1; SMN2MEN1 | |
| SCHEMBL21793990 | 0.71 | ACLY (0.35) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL19634076 | 0.70 | APLNR (0.32) | ALDH1A1QPCTLMNATSPONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |