Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19664384 | 0.87 | KMT2A (0.45) | ALDH1A1L3MBTL1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9663046 | 0.86 | TSHR (0.38) | TSHRKMT2AMAPTLMNAACACB | |
| SCHEMBL9663281 | 0.79 | NPC1 (0.33) | KMT2APOLBMAPTLMNATDP1 | |
| SCHEMBL9199754 | 0.79 | ACACB (0.40) | ALDH1A1TSHRL3MBTL1KMT2AMAPT | |
| SCHEMBL19664382 | 0.78 | TDP1 (0.36) | ALDH1A1THRBL3MBTL1KMT2APOLB | |
| SCHEMBL9662430 | 0.76 | LMNA (0.36) | ALDH1A1KMT2APOLBSMN1; SMN2MAPT | |
| SCHEMBL9196824 | 0.76 | L3MBTL1 (0.38) | ALDH1A1TSHRL3MBTL1KMT2APOLB | |
| SCHEMBL9568958 | 0.76 | AAK1 (0.38) | ALDH1A1KMT2AHSD17B10MEN1ACACB | |
| SCHEMBL1228643 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBKMT2ASMN1; SMN2 | |
| SCHEMBL8782175 | 0.73 | KMT2A (0.54) | ALDH1A1TSHRL3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278452-B1 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| EP-0278452-A2 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |