SCHEMBL19669965

SCHEMBL19669965

C=CC1=C(/C=C\C)c2ccccc2C12c1ccccc1-c1ccccc12

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.36
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22435806 0.98 PDK2 (0.35) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21564256 0.97 PDK2 (0.35) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21867770 0.95 PDK2 (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21868089 0.92 PDK2 (0.33) PDK2
SCHEMBL24688932 0.90 LMNA (0.31) PDK2LMNA
SCHEMBL21120326 0.89 MEN1 (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21152404 0.88 PDK2 (0.39) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL20025734 0.88 PDK2 (0.43) PDK2
SCHEMBL23846067 0.88 PDK2 (0.31) PDK2
SCHEMBL21922630 0.87 PDK2 (0.36) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11731990-B2 Carbazole-based Bodipys for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11730053-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-15 US disclosed
US-11643414-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-05-09 US disclosed
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-20220029122-A1 ORGANIC LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2022-01-27 US disclosed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed
US-10665790-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2020-05-26 US disclosed
US-20200136056-A1 Compound, Light-emitting Lifetime Lengthening Agent, Use of N-type Compound, Film and Light-emitting Device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-04-30 US disclosed
US-9837617-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2017-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200136056-A1 Compound, Light-emitting Lifetime Lengthening Agent, Use of N-type Compound, Film and Light-emitting Device TELO2, NBAS, SMCHD1 PDK2 4573/4885KDM4E 2346/4885MEN1 1733/4885
US-10665790-B2 Materials for electronic devices SDHB, SDHA, ETFB PDK2 178/4885KDM4E 3545/4885MEN1 337/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 PDK2 1181/4885KDM4E 852/4885MEN1 493/4885
US-11643414-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2A1, PIEZO1 PDK2 1227/4885KDM4E 2933/4885MEN1 570/4885
US-11731990-B2 Carbazole-based Bodipys for organic electroluminescent devices CYP1B1, ECI1, FIS1 PDK2 415/4885KDM4E 3933/4885MEN1 1888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.