Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670593 | 0.88 | JAK1 (0.38) | MLNRCNR1 | |
| SCHEMBL19670251 | 0.87 | MLLT1 (0.39) | MLLT1CREBBPMLLT3CNR1TRPV1 | |
| SCHEMBL19670225 | 0.87 | MLLT1 (0.38) | MLLT1CREBBPMLLT3TRPV1MAOA | |
| SCHEMBL19670386 | 0.85 | CACNA1H (0.37) | MLLT1CREBBPCACNA1HMLLT3NOTUM | |
| SCHEMBL19670388 | 0.85 | CACNA1G (0.46) | CACNA1H | |
| SCHEMBL17618483 | 0.83 | KDM1A (0.37) | KDM1ACREBBPMLNRCNR1MAOA | |
| SCHEMBL19670174 | 0.83 | HDAC2 (0.39) | CACNA1HMLNR | |
| SCHEMBL19670170 | 0.82 | BRAF (0.40) | CREBBPCACNA1HCNR1 | |
| SCHEMBL19670172 | 0.82 | ADORA2A (0.37) | MLNR | |
| SCHEMBL19670252 | 0.81 | THRB (0.38) | CACNA1HMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |