Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 7/20 | 0.39 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365640 | 0.91 | MLLT1 (0.37) | MLLT1MLLT3CREBBPMAOBMAOA | |
| SCHEMBL19670225 | 0.87 | MLLT1 (0.38) | MLLT1MLLT3CREBBPMAOBMAOA | |
| SCHEMBL19670253 | 0.87 | MLLT1 (0.38) | MLLT1MLLT3CREBBPMAOBMAOA | |
| SCHEMBL19670386 | 0.85 | CACNA1H (0.37) | MLLT1MLLT3CREBBPNOTUM | |
| SCHEMBL19670393 | 0.85 | ABL1 (0.42) | ALDH1A1MAPTTRPV3ABL1BCR | |
| SCHEMBL17618503 | 0.84 | CREBBP (0.37) | MLLT1CREBBPMAOBMAOAACHE | |
| SCHEMBL19670429 | 0.82 | BRAF (0.40) | CREBBPNPC1RAB9ACNR1 | |
| SCHEMBL19670432 | 0.82 | TRPV3 (0.34) | CREBBPNPC1RAB9ATRPV3ABL1 | |
| SCHEMBL19669985 | 0.81 | KARS1 (0.43) | TRPV3ABL1BCR | |
| SCHEMBL19670242 | 0.80 | SLC27A1 (0.35) | NPC1ALDH1A1MAPTRAB9ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |