Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16250012 | 0.86 | TRPV1 (0.43) | TRPV1GGPS1MEN1KMT2ASYK | |
| SCHEMBL19670218 | 0.86 | MAPT (0.43) | TRPV1MEN1KMT2AADORA2AMCHR1 | |
| SCHEMBL19670141 | 0.85 | SCN9A (0.37) | TRPV1MEN1KMT2AADORA2AHDAC1 | |
| SCHEMBL19670214 | 0.83 | TRPA1 (0.38) | MEN1KMT2ATRPA1TRPV3TRPV4 | |
| SCHEMBL19670580 | 0.83 | TRPV1 (0.43) | TRPV1MEN1KMT2AMCHR1KDM1A | |
| SCHEMBL19670412 | 0.83 | POLB (0.37) | MEN1KMT2ATRPA1TRPV3TRPV4 | |
| SCHEMBL19670179 | 0.82 | HTR2C (0.46) | TRPV1MEN1KMT2A | |
| SCHEMBL19670225 | 0.82 | MLLT1 (0.38) | TRPV1MEN1KMT2AMCHR1MAOA | |
| SCHEMBL19670209 | 0.81 | CNR2 (0.36) | MEN1KMT2ATRPV3ADORA2AKDM1A | |
| SCHEMBL19670644 | 0.81 | HSD17B10 (0.37) | TRPV1MEN1KMT2ATRPV3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |