Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966566 | 0.83 | LMNA (0.44) | TRPM8LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1963663 | 0.81 | MAPT (0.45) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL302170 | 0.69 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1967123 | 0.68 | LMNA (0.68) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL3379808 | 0.67 | ALDH1A1 (0.52) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17075503 | 0.67 | MEN1 (0.60) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3278663 | 0.64 | PTGES (0.84) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL119485 | 0.64 | TRPM8 (0.80) | TRPM8 | |
| SCHEMBL120614 | 0.64 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL17075502 | 0.64 | TAS2R14 (0.62) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | disclosed |