SCHEMBL19690707

SCHEMBL19690707

CCOC(=O)C1(C(=O)OCC)C(c2ccccc2)=C(Cc2ccccc2)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.41
▸ LMNA P02545 7/20 0.41
▸ HPGD P15428 6/20 0.41
▸ MAPT P10636 5/20 0.41
▸ NPSR1 Q6W5P4 5/20 0.41
▸ MEN1 O00255 4/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ ALOX12 P18054 3/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ HTT P42858 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ STAT3 P40763 1/20 0.41
▸ KCNH2 Q12809 1/20 0.41
▸ KDM4E B2RXH2 5/20 0.39
▸ CCR6 P51684 3/20 0.39
▸ HKDC1 Q2TB90 3/20 0.39
▸ KDM4C Q9H3R0 1/20 0.39
▸ TNF P01375 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18663359 0.82 ALDH1A1 (0.43) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL19690389 0.81 SMN1; SMN2 (0.40) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL18663394 0.76 TSHR (0.46) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL9416753 0.76 ALDH1A1 (0.49) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL31598429 0.75 ALDH1A1 (0.42) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL19690413 0.75 SMN1; SMN2 (0.43) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL18663305 0.74 OPRK1 (0.37) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL9416778 0.73 ALDH1A1 (0.46) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL19690521 0.73 SMN1; SMN2 (0.44) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL26792521 0.72 ALDH1A1 (0.46) ALDH1A1LMNAHPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104109212-A Solid catalyst component used for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-10-22 — — CN claimed
CN-104109213-A Catalyst component for olefin polymerization and catalyst thereof BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-10-22 — — CN claimed
CN-104058967-A Unsaturated cyclosubstituted diacid ester compound suitable for preparing olefin polymerization catalyst BEIJING LIHE ZHIXIN TECHNOLOGY LTD 2014-09-24 — — CN claimed
CN-104045748-A Solid catalyst component for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY LTD 2014-09-17 — — CN claimed
CN-104017113-A Catalyst component for olefin polymerization, catalyst containing catalyst component and application of catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-09-03 — — CN claimed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 — — US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 — — US disclosed
CN-104109212-A Solid catalyst component used for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-10-22 — — CN disclosed
CN-104109213-A Catalyst component for olefin polymerization and catalyst thereof BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-10-22 — — CN disclosed
CN-104058967-A Unsaturated cyclosubstituted diacid ester compound suitable for preparing olefin polymerization catalyst BEIJING LIHE ZHIXIN TECHNOLOGY LTD 2014-09-24 — — CN disclosed
CN-104045748-A Solid catalyst component for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY LTD 2014-09-17 — — CN disclosed
CN-104017113-A Catalyst component for olefin polymerization, catalyst containing catalyst component and application of catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-09-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B ALDH1A1 2055/4885LMNA 2302/4885HPGD 2103/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 ALDH1A1 2496/4885LMNA 3701/4885HPGD 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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