Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113042 | 0.86 | TSHR (0.36) | TSHR | |
| SCHEMBL1974644 | 0.85 | DNM1 (0.33) | — | |
| SCHEMBL1973742 | 0.83 | OPRM1 (0.41) | — | |
| SCHEMBL28862050 | 0.81 | ACE2 (0.42) | TSHR | |
| SCHEMBL7537993 | 0.81 | ACE2 (0.42) | TSHR | |
| SCHEMBL28049474 | 0.80 | TSHR (0.39) | TSHR | |
| SCHEMBL17607446 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL20957486 | 0.79 | TSHR (0.42) | TSHR | |
| SCHEMBL597865 | 0.78 | TSHR (0.46) | TSHR | |
| SCHEMBL1969594 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730979-A | Pol theta inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11345680-B2 | Method for producing bispyrrolidine compounds | BASF SE (DE) | 2022-05-31 | — | — | US | disclosed |
| US-20200392115-A1 | METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS | BASF SE (DE) | 2020-12-17 | — | — | US | disclosed |
| EP-3713915-A1 | METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS | BASF SE (DE) | 2020-09-30 | — | — | EP | disclosed |
| CN-111372916-A | Process for producing bispyrrolidine compounds | 巴斯夫欧洲公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2019101568-A1 | METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS | BASF SE (DE) | 2019-05-31 | — | — | WO | disclosed |
| CN-105969543-B | Flue dust cleaning agent after fire | 江苏筑磊电子科技有限公司 | 2019-04-05 | — | — | CN | disclosed |
| US-9469662-B2 | Process for preparing optically active biophosphinylalkanes | BASF SE (DE) | 2016-10-18 | — | — | US | disclosed |
| CN-105969543-A | Smoke dust cleaning agent after fire hazards | 江苏筑磊电子科技有限公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-1913007-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20080242893-A1 | Process for Preparing Optically Active Diphosphanes | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-02 | — | — | US | disclosed |
| EP-0151282-B1 | OPTICALLY ACTIVE 3,4-BIS-(DIPHENYLPHOSPHINO)-PYRROLIDINE, RHODIUM COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS, AND THEIR USE | Degussa Aktiengesellschaft (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0151282-A1 | Optically active 3,4-bis-(diphenylphosphino)-pyrrolidine, rhodium complexes containing them as chiral ligands, and their use | Degussa Aktiengesellschaft (DE) | 1985-08-14 | — | — | EP | disclosed |
| US-4083849-A | Process for preparation of 5-cyanopyrid-6-ones | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392115-A1 | METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS | BBOX1, DHPS, BCKDK | TSHR 4272/4885 |
| US-11345680-B2 | Method for producing bispyrrolidine compounds | BCKDK, BBOX1, DHPS | TSHR 4288/4885 |
| US-20080242893-A1 | Process for Preparing Optically Active Diphosphanes | PHOSPHO1, DCTPP1, DCPS | TSHR 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.