Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939764 | 0.94 | TSHR (0.57) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL23776239 | 0.94 | TSHR (0.52) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL5163665 | 0.94 | TSHR (0.57) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL23775984 | 0.94 | TSHR (0.57) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL23776075 | 0.92 | POLB (0.49) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL23776153 | 0.92 | NOD2 (0.47) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL23775892 | 0.92 | NOD2 (0.50) | ALDH1A1TSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL23775868 | 0.92 | NOD2 (0.50) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL25491469 | 0.90 | AR (0.53) | TSHRGAAKMT2AMEN1KDM4E | |
| SCHEMBL23776099 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRGAASIRT3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-18 | — | — | US | disclosed |
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-18 | — | — | US | disclosed |
| US-20220127226-A1 | ANTI-ARRHYTHMICITY AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-28 | — | — | US | disclosed |
| WO-2021163493-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-19 | — | — | WO | disclosed |
| US-20170362173-A1 | ANTI-ARRHYTHMICITY AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362173-A1 | ANTI-ARRHYTHMICITY AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | CHERP, ATP2A1, ATP2A3 | ALDH1A1 3911/4885TSHR 4002/4885GAA 2628/4885 |
| US-20170362173-A1 | ANTI-ARRHYTHMICITY AGENTS | KCNH1, TNNI3, TNNC1 | ALDH1A1 806/4885TSHR 3461/4885GAA 3270/4885 |
| US-20220127226-A1 | ANTI-ARRHYTHMICITY AGENTS | KCNH1, TNNI3, TNNC1 | ALDH1A1 806/4885TSHR 3461/4885GAA 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.