Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163665 | 1.00 | TSHR (0.57) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL23775984 | 1.00 | TSHR (0.57) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL23776239 | 0.96 | TSHR (0.52) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL25491424 | 0.94 | LMNA (0.50) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL19726324 | 0.94 | ALDH1A1 (0.49) | TSHRGAALMNAKDM4EALDH1A1 | |
| SCHEMBL23775892 | 0.91 | NOD2 (0.50) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL23776075 | 0.91 | POLB (0.49) | TSHRGAANOD2NOD1LMNA | |
| SCHEMBL23775868 | 0.91 | NOD2 (0.50) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL23776146 | 0.90 | TSHR (0.49) | TSHRGAANPSR1NOD2NOD1 | |
| SCHEMBL25491432 | 0.90 | USP2 (0.49) | TSHRGAANPSR1NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025237908-A1 | COMBINATION OF VDAC2 MODULATORS AND BH3 MIMETICS FOR TREATING CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-11-20 | — | — | WO | claimed |
| US-12378193-B2 | Anti-arrhythmicity agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-08-05 | — | — | US | claimed |
| EP-4398892-A1 | CARDIAC ORGANOID AND ANTI-ELECTRO-MITOCHONDRIAL DESYNCHRONIZATION THERAPY | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2024-07-17 | — | — | EP | claimed |
| CN-118302158-A | Cardiac organoids and anti-electro-mitochondrial dyssynchrony therapy | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | WAVEBREAK INC (US) | 2024-06-27 | — | — | US | claimed |
| WO-2023037371-A9 | CARDIAC ORGANOID AND ANTI-ELECTRO-MITOCHONDRIAL DESYNCHRONIZATION THERAPY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-05-16 | — | — | WO | claimed |
| WO-2022212568-A9 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2023-11-16 | — | — | WO | claimed |
| WO-2023062451-A1 | PEGYLATED TAT-EFSEVIN-TA AS AN ANTIARRHYTHMIC AGENT WITH FAVORABLE EFFECT ON HEART FAILURE CAUSED BY ARRHYTHMIA | FARHADI ANDAR ABI ALI (IR) | 2023-04-20 | — | — | WO | claimed |
| WO-2023037371-A1 | CARDIAC ORGANOID AND ANTI-ELECTRO-MITOCHONDRIAL DESYNCHRONIZATION THERAPY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-03-16 | — | — | WO | claimed |
| WO-2022212568-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2022-10-06 | — | — | WO | claimed |
| US-20220127226-A1 | ANTI-ARRHYTHMICITY AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-28 | — | — | US | claimed |
| WO-2025237908-A1 | COMBINATION OF VDAC2 MODULATORS AND BH3 MIMETICS FOR TREATING CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-11-20 | — | — | WO | disclosed |
| US-12378193-B2 | Anti-arrhythmicity agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-08-05 | — | — | US | disclosed |
| WO-2025063845-A1 | DISEASE MODEL | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) | 2025-03-27 | — | — | WO | disclosed |
| US-20240263147-A1 | CARDIAC ORGANOID AND ANTI-ELECTRO-MITOCHONDRIAL DESYNCHRONIZATION THERAPY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-08-08 | — | — | US | disclosed |
| US-7241798-B2 | NK1 antagonists | PFIZER INC. (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1753718-A1 | 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES | Pfizer Products Incorporated (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20050288358-A1 | 3-amino-2-phenylpyrrolidine derivatives | PFIZER INC. | 2005-12-29 | — | — | US | disclosed |
| WO-2005115976-A1 | 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050272800-A1 | NK1 antagonists | PFIZER INC | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288358-A1 | 3-amino-2-phenylpyrrolidine derivatives | PBK, KCND3, KCND2 | TSHR 2900/4885GAA 627/4885NPSR1 230/4885 |
| US-20050272800-A1 | NK1 antagonists | TACR1, TACR2, TAC3 | TSHR 1166/4885GAA 1756/4885NPSR1 9/4885 |
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | CPT2, PC, SREBF2 | TSHR 3831/4885GAA 1034/4885NPSR1 3525/4885 |
| US-12378193-B2 | Anti-arrhythmicity agents | KCNH1, TNNI3, TNNC1 | TSHR 3461/4885GAA 3270/4885NPSR1 1017/4885 |
| US-20220127226-A1 | ANTI-ARRHYTHMICITY AGENTS | KCNH1, TNNI3, TNNC1 | TSHR 3461/4885GAA 3270/4885NPSR1 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.