SCHEMBL19729653

SCHEMBL19729653

c1ccc(-c2cccc(-c3ccccc3)c2-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
MAPK14 Q16539 1/20 0.49
HSD17B10 Q99714 3/20 0.41
HTR6 P50406 2/20 0.40
DUSP3 P51452 1/20 0.40
ALDH1A1 P00352 5/20 0.39
METAP2 P50579 1/20 0.39
GPR3 P46089 1/20 0.38
MAP4K4 O95819 1/20 0.38
CSF1R P07333 1/20 0.38
FGFR1 P11362 1/20 0.38
PDGFRA P16234 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38
CSNK1A1 P48729 1/20 0.38
LIMK1 P53667 1/20 0.38
CDK5 Q00535 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19075903 0.98 L3MBTL1 (0.48) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL12854048 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL19729666 0.91 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL19075908 0.89 ALDH1A1 (0.44) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL19729705 0.89 MAPK14 (0.42) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL24948905 0.89 MAPK14 (0.49) L3MBTL1KDM4EATMMAPK14ALDH1A1
SCHEMBL20968585 0.89 MAPK14 (0.42) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL153607 0.89 ALDH1A1 (0.46) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL31678507 0.89 MAPK14 (0.51) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL19075905 0.88 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPK14HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357150-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-09 US disclosed
US-20230200223-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20220140255-A1 ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-05 US disclosed
US-20170365796-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200223-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SLC1A2, MAOA, SLC18A1 L3MBTL1 520/4885KDM4E 1239/4885ATM 2121/4885
US-20170365796-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 L3MBTL1 958/4885KDM4E 2960/4885ATM 1582/4885
US-20230357150-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE AOX1, CRY1, CYP1A1 L3MBTL1 1123/4885KDM4E 1958/4885ATM 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.