Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23346142 | 0.88 | SLC9A1 (0.33) | KDM4EHPGDSLC9A1HTTMPO | |
| SCHEMBL22513528 | 0.83 | KDM4E (0.34) | KDM4EHPGDSLC9A1HTTMPO | |
| SCHEMBL19738601 | 0.83 | KDM4E (0.37) | KDM4EHPGDSLC9A1HTTMPO | |
| SCHEMBL28718737 | 0.82 | — | — | |
| SCHEMBL10233410 | 0.77 | HPGD (0.42) | KDM4EHPGDSLC9A1HTTATM | |
| SCHEMBL25508949 | 0.76 | LMNA (0.33) | KDM4EHPGDSLC9A1HTTCYP2D6 | |
| SCHEMBL19738627 | 0.75 | KDM4E (0.34) | KDM4EHPGDSLC9A1HTTMPO | |
| SCHEMBL27426760 | 0.73 | KDM4E (0.39) | KDM4EHPGDSLC9A1HTTMAPK1 | |
| SCHEMBL5701125 | 0.73 | TSHR (0.37) | KDM4EHPGDHTTMPOCYP1A2 | |
| SCHEMBL1938057 | 0.72 | CYP1A2 (0.37) | KDM4EHPGDHTTMPOCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11217754-B2 | Organic electroluminescence device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-01-04 | — | — | US | disclosed |
| US-10336735-B2 | Small molecule inhibitors of fibrosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180212153-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-07-26 | — | — | US | disclosed |
| US-20170362211-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212153-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | TYR, SLC18A1, SLC18A3 | KDM4E 1504/4885HPGD 1884/4885SLC9A1 599/4885 |
| US-10336735-B2 | Small molecule inhibitors of fibrosis | MMP1, COL2A1, MMP8 | KDM4E 2499/4885HPGD 1026/4885SLC9A1 3361/4885 |
| US-20170362211-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | MMP1, COL2A1, MMP8 | KDM4E 2499/4885HPGD 1026/4885SLC9A1 3361/4885 |
| US-11217754-B2 | Organic electroluminescence device | TYR, SLC18A1, SLC18A3 | KDM4E 1504/4885HPGD 1884/4885SLC9A1 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.