Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975415 | 0.76 | TSHR (0.35) | TSHRNPSR1CA9CA12CA1 | |
| SCHEMBL1974456 | 0.75 | POLB (0.46) | TSHRLMNAALDH1A1HTTMEN1 | |
| SCHEMBL1978010 | 0.75 | SMN1; SMN2 (0.37) | TSHRNPSR1CA9CA12CA1 | |
| SCHEMBL7757228 | 0.73 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8571742 | 0.71 | VCAM1 (0.37) | TSHRNPSR1CA9CA12CA1 | |
| SCHEMBL7757769 | 0.70 | VCAM1 (0.36) | TSHRNPSR1CA9CA12CA1 | |
| SCHEMBL27741307 | 0.70 | HSD11B1 (0.34) | CA9CA12ALDH1A1MEN1KMT2A | |
| SCHEMBL9720805 | 0.69 | ENPP2 (0.42) | KMT2ANPC1 | |
| SCHEMBL7870277 | 0.68 | PGK1 (0.44) | TSHRALDH1A1MEN1KMT2APKM | |
| SCHEMBL2415090 | 0.66 | SIGMAR1 (0.47) | TSHRLMNAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658129-B2 | Agents and methods for the imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | TSHR 4269/4885NPSR1 3241/4885CA9 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.