Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975415 | 0.80 | TSHR (0.35) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL7757228 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2TSHRALDH1A1VCAM1NCF1 | |
| SCHEMBL8571742 | 0.77 | VCAM1 (0.37) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL7757769 | 0.76 | VCAM1 (0.36) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL1975417 | 0.75 | TSHR (0.39) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL2415090 | 0.75 | SIGMAR1 (0.47) | SMN1; SMN2LMNAHTTRAB9ATSHR | |
| SCHEMBL9701756 | 0.74 | DUT (0.36) | TSHRALDH1A1 | |
| SCHEMBL1975782 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTTRAB9ATSHR | |
| SCHEMBL2468075 | 0.70 | LMNA (0.66) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL2981195 | 0.70 | TRPA1 (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658129-B2 | Agents and methods for the imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | SMN1; SMN2 278/4885LMNA 472/4885HTT 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.