Sugi Predict

Sugi Predict / Compounds / SCHEMBL1978237

SCHEMBL1978237

SCHEMBL1978237

COc1ccc2c(c1)CCc1cc(OC)cc(OC)c1-2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.48
▸ MAPT P10636 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ CYP1A2 P05177 3/20 0.48
▸ CYP2D6 P10635 2/20 0.48
▸ MPO P05164 1/20 0.47
▸ CYP3A4 P08684 2/20 0.47
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ CA7 P43166 1/20 0.47
▸ CA9 Q16790 1/20 0.47
▸ CA14 Q9ULX7 1/20 0.47
▸ PTGS2 P35354 1/20 0.46
▸ EGFR P00533 2/20 0.46
▸ CYP1A1 P04798 1/20 0.46
▸ CYP2E1 P05181 1/20 0.46
▸ CYP2C8 P10632 1/20 0.46
▸ CYP2A6 P11509 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30897586 1.00 ALDH1A1 (0.48) ALDH1A1MAPTMAPK1SMN1; SMN2CYP1A2
SCHEMBL28816492 0.87 PTGS2 (0.56) ALDH1A1CYP1A2CYP3A4PTGS2EGFR
SCHEMBL23754278 0.87 PTGS2 (0.56) ALDH1A1CYP1A2CYP3A4PTGS2EGFR
Coelonin SCHEMBL31696771 0.87 PTGS2 (0.64) ALDH1A1MAPTMAPK1SMN1; SMN2CYP1A2
Coelonin SCHEMBL23203411 0.87 PTGS2 (0.64) ALDH1A1MAPTMAPK1SMN1; SMN2CYP1A2
SCHEMBL30529912 0.84 PTGS2 (0.55) ALDH1A1MAPTCYP1A2CYP2D6CYP3A4
SCHEMBL17108416 0.81 MPO (0.59) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2D6
SCHEMBL23142694 0.79 MIF (0.54) ALDH1A1MAPTMAPK1SMN1; SMN2CYP1A2
SCHEMBL23203428 0.79 ALDH1A1 (0.48) ALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL3141978 0.76 MPO (0.54) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117959276-A A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application 广西仙手棋药业科技有限公司 2024-05-03 — — CN claimed
CN-117959276-A A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application 广西仙手棋药业科技有限公司 2024-05-03 — — CN disclosed
EP-3999130-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID United Health Products, Inc. (US) 2022-05-25 — — EP disclosed
US-20210015964-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID UNITED HEALTH PRODUCTS INC (US) 2021-01-21 — — US disclosed
WO-2021011940-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID UNITED HEALTH PRODUCTS, INC. (US) 2021-01-21 — — WO disclosed
US-20140046277-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC. 2014-02-13 — — US disclosed
US-8557874-B2 Hemostatic material EPIC WOUND CARE, INC. (US) 2013-10-15 — — US disclosed
EP-1803473-B1 Adhesive including medicament UNIV LOMA LINDA MED (US) 2011-06-22 — — EP disclosed
CN-1835723-B Deployable multifunctional hemostatic agent UNIV LOMA LINDA MED 2011-06-22 — — CN disclosed
WO-2009070684-A2 HEMOSTATIC MATERIAL BAGGETT RICHARD W (US) 2009-06-04 — — WO disclosed
US-20080031929-A1 LIQUID BANDAGE MEDSPRING GROUP, INC. 2008-02-07 — — US disclosed
EP-1803473-A2 Adhesive including medicament Loma Linda University Medical Center (US) 2007-07-04 — — EP disclosed
US-20070026052-A1 Hemostatic material UNITED ECOENERGY CORP. 2007-02-01 — — US disclosed
CN-1835723-A Deployable multifunctional hemostatic agent UNIV LOMA LINDA MED (US) 2006-09-20 — — CN disclosed
EP-1638491-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT Loma Linda University Medical Center (US) 2006-03-29 — — EP disclosed
US-20050123588-A1 Deployable multifunctional hemostatic agent LOMA LINDA UNIVERSITY MEDICAL CENTER 2005-06-09 — — US disclosed
WO-2005002510-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT LOMA LINDA UNIVERSITY MEDICAL CENTER (US) 2005-01-13 — — WO disclosed
EP-1409033-A1 ADHESIVE INCLUDING MEDICAMENT Loma Linda University Medical Center (US) 2004-04-21 — — EP disclosed
US-20030044380-A1 Adhesive including medicament LOMA LINDA UNIVERSITY 2003-03-06 — — US disclosed
WO-2003008003-A1 ADHESIVE INCLUDING MEDICAMENT LOMA LINDA UNIVERSITY MEDICAL CENTER (US) 2003-01-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044380-A1 Adhesive including medicament ICAM1, VCAM1, EPCAM ALDH1A1 473/4885MAPT 3022/4885MAPK1 4331/4885
US-20080031929-A1 LIQUID BANDAGE FGB, F2, F8 ALDH1A1 2642/4885MAPT 3724/4885MAPK1 4222/4885
US-20050123588-A1 Deployable multifunctional hemostatic agent FGB, CHIT1, CHIA ALDH1A1 3379/4885MAPT 3796/4885MAPK1 4055/4885
US-20070026052-A1 Hemostatic material F2, F8, F3 ALDH1A1 2436/4885MAPT 3651/4885MAPK1 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.