Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15466082 | 0.71 | RXRA (0.47) | ALDH1A1ALOX15TSHRHSD17B10ADRA2A | |
| SCHEMBL1254154 | 0.71 | RXRA (0.47) | HTR1AHTR7HTR2AHTR6CA1 | |
| SCHEMBL14501784 | 0.70 | SIGMAR1 (0.46) | HTR1AALDH1A1OPRD1 | |
| Hydrochloric Acid SCHEMBL2864663 | 0.70 | RXRA (0.46) | CA1CA2ACHEALDH1A1ALOX15 | |
| SCHEMBL24105589 | 0.69 | LMNA (0.37) | HTR1AHTR7HTR2AHTR6DRD2 | |
| SCHEMBL8929737 | 0.69 | PLAU (0.56) | HTR1ACA1CA2GRIN2BTSHR | |
| SCHEMBL14596264 | 0.68 | HTR2A (0.37) | HTR1AHTR7HTR2AHTR6ALDH1A1 | |
| SCHEMBL21340218 | 0.68 | ASIC3 (0.55) | DRD2DRD3ADRA2AADRA2BADRA2C | |
| SCHEMBL2577433 | 0.67 | HTR2C (0.53) | HTR2ADRD2DRD1ADRA2AADRA2B | |
| SCHEMBL18457176 | 0.67 | ALDH1A1 (0.39) | HTR1AHTR7HTR2AHTR6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |